Location: Plum St and 6th St, Cincinnati
As 22/3 join in a truly unnecessary redundant concurrency, all three lanes will turn right. Use the leftmost lane to stay on the US routes. Use the middle lane to merge onto US 50/SR 264 west. Keep right for I-75 north.
Location: Plum St and 6th St, Cincinnati
Keep right for I-75 north and stay in the middle lane for 50/264 west.
Location: 6th St and Central Ave, Cincinnati
Turn left at the light to stay on the four US routes south/eastbound to connect to US 50 east, I-71 north, and I-71/75 south, which do not have direct connection at this interchange.
Location: 6th St and Central Ave, Cincinnati
If you don’t turn, keep right for I-75 north. Use the rightmost left lane for SR 264 west and the leftmost lane for US 50 west. US 22 and Ohio 3 end here.
N to US-42, S to US-42/US-127
N to I-71/I-471/US-22/OH-3, S to US-27/US-52
N to US-42, S to US-27/US-52
N to I-71/I-471/US-42
S to KY State Line, N to US-50
S to KY State Line, N to I-74
W to OH-264, E to I-71
N to US-42
W to US-50
E to I-71/I-471/US-42, W to I-71/I-75/US-27/US-42/US-50/US-52/US-127/OH-3/OH-264
N to I-71/I-471/US-42, S to I-71/I-75/US-22/US-27/US-42/US-50/US-52/US-127/OH-264
