Location: US 45 and Main St, Tupelo
Just after the MS 6 split we’ll approach MS 178.
Location: US 45 and Front St, Tupelo
Exit left ahead for MS 178 west. Stay in the center lane to follow US 45 to I-22.
Location: US 45 and McCullough Blvd, Tupelo
Exit left for MS 178 west.
N to I-22/US-78, S to US-278/MS-6
W to I-22/US-78
E to MS-178, W to US-45/US-278
