U.S. Route 45, MS-6 to MS-178


Location: US 45 and Main St, Tupelo

Just after the MS 6 split we’ll approach MS 178.

Location: US 45 and Front St, Tupelo

Exit left ahead for MS 178 west. Stay in the center lane to follow US 45 to I-22.

Location: US 45 and McCullough Blvd, Tupelo

Exit left for MS 178 west.

 N to I-22/US-78, S to US-278/MS-6

 W to I-22/US-78

 E to MS-178, W to US-45/US-278